NOT KNOWN FACTUAL STATEMENTS ABOUT NR1-SITE

Employing this strategy, Kalbaugh et al. assigned affinity and efficacy roles to positions during the LBDs on the NR1 and NR2A NMDAR subunits. In situ mutation of residues in immediate connection with bound ligand afflicted the two efficacy and affinity, even though positions that stabilize the closed cleft conformation without a immediate ligand c